研究成果

技術標準引領

序號

標準名稱

標準編號

標準詳情(全國團體標準信息平臺)

1

保健食品潤腸通便功能的斑馬魚檢測方法

T/ZHCA 501-2020

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2

保健食品抗氧化功能的斑馬魚檢測方法

T/ZHCA 502-2020

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3

保健食品功能評價 斑馬魚試驗規程

T/CHC2003 -2022

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4

化妝品美白功效測試 斑馬魚胚胎黑色素抑制功效測試方法

T/ZHCA 012-2021

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5

化妝品抗皺功效評價 斑馬魚幼魚尾鰭皺縮抑制率法

T/ZHCA 014-2022

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6

化妝品緊致功效評價 斑馬魚幼魚彈性蛋白基因相對表達量法

T/ZHCA 015-2022

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7

化妝品舒緩功效評價 斑馬魚幼魚中性粒細胞抑制率法

T/ZHCA 016-2022

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8

禽肉的斑馬魚胚胎生物效應測試方法

T/CMATB11001-2021

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9

GB/T 39649-2020 實驗動物 實驗魚質量控制

GB/T 39649-2020

2022年

10

降血脂食品斑馬魚檢測技術團體標準

制訂中

2022年

11

斑馬魚用于中藥生物效應評價技術指南與團體標準

制訂中

2022年

12

食用農產品營養品質評價 斑馬魚卵法

已過評審

2022年

 

部分技術專利

序號

專利名稱

專利號

申請日期

1

一種評價藥物預防病毒性肺炎的方法

ZL 202010901213.7

2020.08.31

2

一種檢測保健食品緩解焦慮功效的方法

ZL 202010885827.0

2020.08.28

3

一種適用于評價多種保健食品改善睡眠功效的方法

ZL 202010783803.4

2020.08.06

4

一種用斑馬魚評價肉制品安全性的方法

ZL 202010257281.4

2020.04.03

5

一種用斑馬魚評價乳制品睡眠改善功效的方法

ZL 202010256242.2

2020.04.02

6

用斑馬魚鰾損傷炎癥模型評價肺損傷治療劑與誘導劑的方法

ZL 201610956504.X

2016.11.03

7

一種用斑馬魚評價心肌損傷誘導劑毒性與治療劑功效的方法

ZL 201610969159.3

2016.11.03

8

一種抗PM2.5咀嚼片及其制備方法

ZL 201610216744.6

2016.04.06

9

天然抗癲癇活性化合物及其在藥物制劑中的用途(合作)

ZL 201410487432.X

2014.09.22

10

一種斑馬魚體內ROS檢測模型的建立方法及其應用

ZL 201310398791.3

2013.09.05

11

一種斑馬魚類過敏檢測模型的建立及其應用

ZL 201310262123.8

2013.06.27

12

建立斑馬魚腸蠕動模型及篩選促胃腸動力藥物的方法

ZL 201310181252.4

2013.05.15

13

舒洛地爾在制備抗血管生成類藥物中的應用

ZL 201310020569.X

2013.01.18

14

左旋沙丁胺醇在制備抗血管生成類藥物中的應用

ZL 201310008036.X

2013.01.09

15

一種能抗血管生成的化合物及其用途

ZL 201210562409.3

2012.12.18

16

一種斑馬魚細菌感染模型的構建方法及其應用

ZL 201210377599.1

2012.09.27

17

斑馬魚多發性硬化癥模型的建立方法及其應用

ZL 201210016072.6

2012.01.18

18

斑馬魚P-糖蛋白抑制劑篩選模型的建立方法及其應用

ZL 201110231726.2

2011.08.12

19

建立斑馬魚血栓模型的方法

ZL 201110126427.2

2011.05.17

20

在整體斑馬魚上進行酶聯免疫吸附檢測的方法及應用

ZL 201010547814.9

2010.11.17

21

一種利用斑馬魚篩選線粒體靶向化合物的方法

ZL 201010296696.9

2010.09.29

 

部分論文專著

序號

論文/文章專著(點擊標題可查看詳情)

作者

發表刊物

發表年份

1

Fenobucarb induces heart failure and cerebral hemorrhage in zebrafish

Xiao-Yu Zhu, Bo Xia, Yu-Ying Wu, Hua Yang, Chun-Qi Li, Ping Li

AQUATIC TOXICOLOGY

2019

2

Sensitization and synergistic anticancer efects of Furanodiene identifed in zebrafsh models

Xiao-Yu Zhu, Dian-WuGuo, Qiao-Cong Lao, Yi-QiaoXu, Zhao-Ke Meng, BoXia, HuaYang, Chun-Qi Li & Ping Li

Scientific Reports

2019

3

A Zebrafish Heart Failure Model for Assessing Therapeutic Agents

Xiao-Yu Zhu, Si-Qi Wu, Sheng-Ya Guo, Hua Yang, Bo Xia, Ping Li, and Chun-Qi Li

ZEBRAFISH

2018

4

The Tilapia collagen peptide mixture TY001 protects against LPS-induced inflammation, disruption of glucose metabolism, and aberrant expression of circadian clock genes in mice

Xiao-Yun Xiong, Jun Liang, Yi-Qiao Xu & Yi Liu

CHRONOBIOLOGY INTERNATIONAL

2019

5

Development of zebrafish demyelination model for evaluation of remyelination compounds and RORγt inhibitors

Xiao-Yu Zhu, Sheng-Ya Guo, Bo Xia, Chun-Qi Li, Lei Wang, Yong-Hui Wang

Journal of Pharmacological and Toxicological Methods

2019

6

The wound healing effects of the Tilapia collagen peptide mixture TY001 in streptozotocin diabetic mice

Xiaoyun Xiong, Jun Liang, Yiqiao Xu, Jie Liu, Yi Liu

J Sci Food Agric

2020

7

Fenobucarb-induced developmental neurotoxicity and mechanisms in zebrafish

Xiao-Yu Zhu, Yu-Ying Wu, Bo Xia, Ming-Zhu Dai, Yan-Feng Huang, Hua Yang, Chun-Qi Li, Ping Li

Neurotoxicology

2020

8

A natural complex product Yaocha reduces uric acid level in a live zebrafish model

Xiao-Yun Xiong, Jun Liang, Sheng-Ya Guo, Ming-Zhu Dai, Jia-Li Zhou, Yong Zhang, Yi Liu

Journal of Pharmacological and Toxicological Methods

2020

9

Dammarane-Type Triterpenoids from the Roots of Rhus chinensis and Their Preventive Effects on Zebrafish Heart Failure and Thrombosis

Miao Ye, Wen Xu, Da-Qing He, Xian Wu, Wen-Fang Lai, Xiao-Qin Zhang, Yu Lin, Wei Xu, and Xu-Wen Li

journal of natural products

2020

10

Ponatinib-induced ischemic stroke in larval zebrafish for drug screening

Xiao-Yu Zhu, Bo Xia, Ting Ye, Ming-Zhu Dai, Hua Yang, Chun-Qi Li, Ping Li

European Journal of Pharmacology

2020

11

Developmental neurotoxicity and toxic mechanisms induced by olaquindox in zebrafish

Sheng-Ya Guo, Yong Zhang, Xiao-Yu Zhu, Jia-Li Zhou, Jiao Li, Chun-Qi Li, Li-Ren Wu

JOURNAL OF APPLIED TOXICOLOGY

2020

12

The protection of indolealkylamines from LPS-induced inflammation in zebrafish

Yu Zhang, Norio Takagi, Bo Yuan, Yanyan Zhou, Nan Si, Hongjie Wang, Jian Yang, Xiaolu Wei, Haiyu Zhao, Baolin Bian

Journal of Ethnopharmacology

2019

13

Cardiotoxicity induced by Cochinchina momordica seed extract in zebrafish

Zheng-Cai Du, Zhong-Shang Xia, Yan-Feng Huang, Yi Peng, Bing-Bing Cao, Chun-Qi Li, Yun-Fei Liang, Fang-Hui Zhao, Ming-Zhe Zhang, Zhang-Mei Chen, Xiao-Tao Hou, Er-Wei Hao, Jia-Gang Deng

JOURNAL OF APPLIED TOXICOLOGY

2020

14

Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model

Yubo Guo, Yingyi Fan, Xiaohua Pei

Cancer Medicine

2020

15

Sea Cucumber Intestinal Peptide Induces the Apoptosis of MCF-7 Cells by Inhibiting PI3K/AKT Pathway

Wei Wei, Xiao-Man Fan, Shao-Hui Jia, Xi-Ping Zhang, Zhao Zhang, Xue-Jun Zhang, Jiu-Xun Zhang and Ye-Wang Zhang

frontiers in nutrition

2021

16

Systems Pharmacology and Verification of ShenFuHuang Formula in Zebrafish Model Reveal MultiScale Treatment Strategy for Septic Syndrome in COVID-19

Tengwen Liu, Yuhong Guo, Jingxia Zhao, Shasha He, Yunjing Bai, Ning Wang, Yan Lin, Qingquan Liu, and Xiaolong Xu

frontiers in pharmacology

2020

17

Sanggenon C Stimulates Osteoblastic Proliferation and Differentiation, Inhibits Osteoclastic Resorption, and Ameliorates Prednisone-Induced Osteoporosis in Zebrafish Model

Huijuan Wang, Tingting Feng, Donggui Guo, Min Zhang, Lin Chen and Ying Zhou

molecules

2018

18

Lentinan Impairs the Early Development of Zebrafish Embryos, Possibly by Disrupting Glucose and Lipid Metabolism

Wenyu Miao, Lingling He, Tao Zhang and Chunqi Li

processes

2022

19

Bifidobacterium lactis BL-99 modulates intestinal inflammation and functions in zebrafish models

Meng Chen, Chinfeng Liu, Mingzhu Dai, Qinwen Wang, Chunqi Li, Weilian Hung

plos one

2022

20

Ferroptosis is partially responsible for dexamethasone-induced T cell ablation, but not osteoporosis in larval zebrafish

Wenyu Miao, Lingling He, Yong Zhang, Xiaoyu Zhu, Yangming Jiang, Pengpeng Liu, Tao Zhang, Chunqi Li

Ecotoxicology and Environmental Safety

2022

 

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